PATHOLOGY

Detailed explanation-1: -Memory B lymphocytes. Bm lymphocytes are cells involved in the secondary innate humoral immune response. They also, like other B cells, produce antibodies after the first exposure with an antigen and then produce large amounts of antibodies shortly after another exposure to the same antigen [77].

Detailed explanation-2: -Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia-and Ia+ helper T cells-PMC.

Detailed explanation-3: -In secondary responses, on antigen rechallenge, memory B cells are activated and have at least two fates: they either differentiate into long-lived plasma cells or enter GCs to undergo rounds of population expansion, SHM and selection (Fig.

Detailed explanation-4: -T cells are part of the immune system and develop from stem cells in the bone marrow. They help protect the body from infection and may help fight cancer. Also called T lymphocyte and thymocyte.