PATHOLOGY

Detailed explanation-1: -Lymph nodes are small bean-shaped tissues found along the lymphatic vessels. The lymph nodes act as filters. Various immune system cells trap germs in the lymph nodes and activate the creation of special antibodies in the blood.

Detailed explanation-2: -The lymph nodes monitor the lymph flowing into them and produce cells and antibodies which protect our body from infection and disease.

Detailed explanation-3: -Medullary B lymphocytes are antibody-producing effector cells, i.e. plasmablasts and mature plasma cells. Antigens which have penetrated the surface defense barriers usually reach the lymph nodes via the afferent lymphatic vessels (Figure 4).

Detailed explanation-4: -Lymph node structure The outer layer (Cortex) contains the B-cell areas, or follicles. The middle layer (Paracortex) is mostly populated by T cells and dendritic cells (Figure 1). The paracortex also contains specialised blood vessels (high endothelial venules) through which many B and T cells enter the node.