PATHOLOGY

Detailed explanation-1: -Erythropoiesis (from Greek ‘erythro’ meaning “red” and ‘poiesis’ “to make") is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell.

Detailed explanation-2: -Mature red blood cells (RBCs) or erythrocytes/erythroid cells in a complex process called erythropoiesis are produced from hematopoietic stem cells (HSCs) [5, 6, 7]. Erythroblasts (precursors of RBCs) are difficult to proliferate in vitro [2, 8, 9].

Detailed explanation-3: -Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow are called hemocytoblasts. They give rise to all of the formed elements in blood.

Detailed explanation-4: -Reticulocyte is an immature red blood cell, while erythrocyte is a mature red blood cell.