PATHOLOGY

Detailed explanation-1: -Macrophages and neutrophils display a variety of cell-surface receptors that enable them to recognize and engulf pathogens.

Detailed explanation-2: -Macrophages and neutrophils (phagocytes) are the front-line defenders in your body’s immune system. They seek out, ingest, and destroy pathogens and other debris through a process called phagocytosis.

Detailed explanation-3: -Macrophages are considered to be the primary phagocytes responsible for clearing dead cells in most organs. Macrophages are equipped with a battery of receptors to recognize, bind and engulf apoptotic cells.

Detailed explanation-4: -In addition, macrophages play an important role in eliminating diseased and damaged cells through their programmed cell death. Generally, macrophages ingest and degrade dead cells, debris, tumor cells, and foreign materials.

Detailed explanation-5: -Any cell that undergoes phagocytosis, a process in which pathogens and other foreign particles and debris are engulfed by a cell to be destroyed, is considered a phagocyte. Most phagocytes are types of white blood cells that use phagocytosis to perform basic innate immune system function within the body.