PATHOLOGY

PATHOLOGY MCQ

IMMUNE RESPONSE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which cells have the ability to target cells that are infected by a virus?
A
Cytotoxic T cells
B
B cells
C
Macrophages
D
mast cells
Explanation: 

Detailed explanation-1: -Cytotoxic T cells kill target cells bearing specific antigen while sparing neighboring uninfected cells. All the cells in a tissue are susceptible to lysis by the cytotoxic proteins of armed effector CD8 T cells, but only infected cells are killed.

Detailed explanation-2: -Cytotoxic T Cells These cells (1) express the CD8 coreceptor and (2) destroy infected cells in an antigen-specific manner that depends on the expression of MHC class I molecules on APCs. CTLs are able to kill target cells directly by inducing apoptosis.

Detailed explanation-3: -There are two main types of T-cells: Helper T-cells stimulate B-cells to make antibodies and help killer cells develop. Killer T-cells or cytotoxic T-cells directly kill cells that have already been infected by a foreign invader.

Detailed explanation-4: -Killer T-cells are able to find the cells with viruses and destroy them. Antigens work like identification tags that give your immune system information about your cells and any intruders.

There is 1 question to complete.