PATHOLOGY

Detailed explanation-1: -Answer and Explanation: Fever is not the first line of defense; it is considered the second line of defense. Suppose the first line of defense couldn’t protect the body, and the pathogen still enters the body. In that case, the second line of defense protects the body, including fever, inflammation, and phagocytosis.

Detailed explanation-2: -Innate immune cells are the body’s first line of defense. They quickly respond to foreign cells to fight infection, battle a virus or defend the body against bacteria. T-cells and B-cells react when invading organisms slip through that first line using a process called acquired immunity (or adaptive immunity).

Detailed explanation-3: -The first line of defence (or outside defence system) includes physical and chemical barriers that are always ready and prepared to defend the body from infection. These include your skin, tears, mucus, cilia, stomach acid, urine flow, ‘friendly’ bacteria and white blood cells called neutrophils.

Detailed explanation-4: -Helper T cells are arguably the most important cells in adaptive immunity, as they are required for almost all adaptive immune responses. They not only help activate B cells to secrete antibodies and macrophages to destroy ingested microbes, but they also help activate cytotoxic T cells to kill infected target cells.