PATHOLOGY

Detailed explanation-1: -It does this through a nonspecific immune response known as inflammation. Inflammation, which is sometimes called the inflammatory response, is initiated by a special type of white blood cell called a mast cell. Mast cells detect injury or infection and respond by releasing a chemical called histamine.

Detailed explanation-2: -Nonspecific responses that alter the intracellular environment include fever, inflammation, and interferon.

Detailed explanation-3: -Histamine affects the maturation of immune system cells and alters their activation, polarization, chemotaxis, and effector functions. Histamine also regulates antigen-specific TH1 and TH2 cells, as well as related antibody isotype responses.

Detailed explanation-4: -Histamine is released from cells in response to an antibody called immunoglobulin E (IgE). This antibody may be secreted in response to an invading pathogen such as a virus, bacteria, or an allergenic substance such as pollen. Histamine can also be released in response to injury caused by toxins.

Detailed explanation-5: -So, the correct answer is ‘Killer T-cells’.