PATHOLOGY

Detailed explanation-1: -In adaptive immunity, antigen-presenting cells (APCs) play a crucial role. T-lymphocytes require these to operate properly. B-lymphocytes, macrophages, and dendritic cells are the three primary antigen-presenting cells.

Detailed explanation-2: -A type of immune cell that boosts immune responses by showing antigens on its surface to other cells of the immune system. An antigen-presenting cell is a type of phagocyte. Also called APC.

Detailed explanation-3: -Although dendritic cells are important in presenting antigen, particularly to initiate primary immune responses, macrophages are the professional APC type most prominent in inflammatory sites and specialized for clearing necrotic and apoptotic material.

Detailed explanation-4: -Dendritic cells (DCs) are critical for the activation of naïve CD4+ T cells and are considered professional antigen presenting cells (APCs), as are macrophages and B cells.