PATHOLOGY

Detailed explanation-1: -Phagocytic cells consist of granulocytes (i.e., neutrophils, eosinophils, basophils, and mast cells), monocytes/macrophages, and dendritic cells. These cells participate in not only the phagocytosis but also the inflammatory process.

Detailed explanation-2: -Macrophages are effector cells of the innate immune system that phagocytose bacteria and secrete both pro-inflammatory and antimicrobial mediators. In addition, macrophages play an important role in eliminating diseased and damaged cells through their programmed cell death.

Detailed explanation-3: -Macrophages are specialised cells involved in the detection, phagocytosis and destruction of bacteria and other harmful organisms. In addition, they can also present antigens to T cells and initiate inflammation by releasing molecules (known as cytokines) that activate other cells.

Detailed explanation-4: -Nonspecific defenses include anatomic barriers, inhibitors, phagocytosis, fever, inflammation, and IFN.

Detailed explanation-5: -Innate, or nonspecific, immunity is the defense system with which you were born. It protects you against all antigens. Innate immunity involves barriers that keep harmful materials from entering your body. These barriers form the first line of defense in the immune response.