PATHOLOGY MCQ
INFECTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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B3.1 Which cells are activated in the secondary immune response?
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B cells
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Y cells
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Memory cells
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T cells
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Explanation:
Detailed explanation-1: -In secondary responses, on antigen rechallenge, memory B cells are activated and have at least two fates: they either differentiate into long-lived plasma cells or enter GCs to undergo rounds of population expansion, SHM and selection (Fig.
Detailed explanation-2: -These cells develop within germinal centers of the secondary lymphoid organs. The most important function of memory B cells is to remember the first encounter with invading pathogens, and to provide effective protection against secondary infection for years (Crotty et al., 2003).
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