PATHOLOGY

Detailed explanation-1: -PNN are the first to appear in the inflammatory focus and their main function is to reveal the presence or the absence of the infection, localization and destruction of bacteria.

Detailed explanation-2: -Cell types in inflammatory responses The first cells attracted to a site of injury are neutrophils, followed by monocytes, lymphocytes (natural killer cells [NK cells], T cells, and B cells), and mast cells [71–73].

Detailed explanation-3: -Typically, neutrophils are the first responders to be recruited and have a higher microbicidal activity; whereas monocytes/macrophages are recruited later on.

Detailed explanation-4: -Neutrophils comprise 50% to 70% of circulating leukocytes and represent the body’s initial line of defense. They are involved in the acute inflammatory response to bacterial infection and removal of the bacteria by phagocytosis. They are also the most numerous cells to arrive at the site of injury or infection.

Detailed explanation-5: -Neutrophils, eosinophils, and basophils are all granulocytes because they contain granules. The granules in a neutrophil are small, numerous, and are stained a light-pink to bluish-purple, “neutral” color. The cytoplasm of a neutrophil is light pink.