PATHOLOGY

Detailed explanation-1: -The fact that dead cells induce inflammation indicates that the cell corpse must expose or release some sort of proinflammatory signal(s). It is theoretically possible that this signal(s) might be induced while a cell is dying but still metabolically active.

Detailed explanation-2: -Necrosis, necroptosis, and inflammation. Traditionally, necrosis is considered the primary form of cell death caused by inflammation. Necrosis was historically viewed as an accidental subroutine, largely resulting from very harsh physicochemical stimuli, including abrupt changes in temperature, osmotic pressure, or pH.

Detailed explanation-3: -The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged cells release chemicals including histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling.

Detailed explanation-4: -Apoptosis, in contrast to necrosis, is not harmful to the host and does not induce any inflammatory reaction.