PATHOLOGY

Detailed explanation-1: -Inflammation is the immune system’s response to harmful stimuli, such as pathogens, damaged cells, toxic compounds, or irradiation [1], and acts by removing injurious stimuli and initiating the healing process [2]. Inflammation is therefore a defense mechanism that is vital to health [3].

Detailed explanation-2: -Inflammation is a defense mechanism and it is beneficial – inflammation protects our bodies from infection and injury. However, excessive inflammation can lead to collateral damage, and that’s why we use medicines to reduce it.

Detailed explanation-3: -The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged cells release chemicals including histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling.

Detailed explanation-4: -The primary goal of the inflammatory response is to detect and eliminate factors that interfere with homeostasis.