PATHOLOGY

Detailed explanation-1: -The innate immune system is the body’s first line of defense against germs entering the body. It responds in the same way to all germs and foreign substances, which is why it is sometimes referred to as the “nonspecific” immune system.

Detailed explanation-2: -Skin is a barrier that serves as one of the body’s first lines of defense against harmful microbes. Specialized immune cells within skin tissue help to fight invading organisms. Yet the skin hosts diverse communities of beneficial bacteria, collectively known as the skin microbiota.

Detailed explanation-3: -Physical and chemical barriers form the first line of defense when the body is invaded. The skin has thick layer of dead cells in the epidermis which provides a physical barrier. Periodic shedding of the epidermis removes microbes. The mucous membranes produce mucus that trap microbes.