PATHOLOGY

Detailed explanation-1: -The hyperemic response probably reflects an initial reaction of arterioles to injury and to the rapid release of vasoactive mediators (histamine, bradykinin, neuropeptides, prostaglandins) produced by mast cells, macrophages, fibroblasts, parenchymal cells, and the vessel wall.

Detailed explanation-2: -Vasoconstriction is the initial response whenever there is vessel injury. Vasospasm of the blood vessels occurs first in response to injury of the vasculature. This vasospasm, in turn, stimulates vasoconstriction.

Detailed explanation-3: -The body always responds to an injury with a predictable inflammatory response, as the first step towards healing. Redness, heat, swelling and pain are associated with this first stage. Redness and heat are caused by increased blood flow.

Detailed explanation-4: -Vasodilation. Increased Vascular Permeability. Leukocyte Migration to the Tissues. 17-Jan-2023