PATHOLOGY

PATHOLOGY MCQ

INFLAMMATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which cell plays a major role in chronic inflammation by performing a wide range of functions?
A
Lymphocyte
B
Macrophage
C
Plasma cells
D
Mast cells
Explanation: 

Detailed explanation-1: -In inflammation, macrophages have three major function; antigen presentation, phagocytosis, and immunomodulation through production of various cytokines and growth factors. Macrophages play a critical role in the initiation, maintenance, and resolution of inflammation.

Detailed explanation-2: -Lymphocytes including T-lymphocytes and B-lymphocytes are the next line of defense, and they play a crucial role in mediating inflammation by several complex mechanisms including secreting of cytokines, costimulation of lymphocytes, and production of antibodies and immune complexes.

Detailed explanation-3: -Macrophages are effector cells of the innate immune system that phagocytose bacteria and secrete both pro-inflammatory and antimicrobial mediators. In addition, macrophages play an important role in eliminating diseased and damaged cells through their programmed cell death.

Detailed explanation-4: -Macrophages. Endothelial cells. Fibroblasts. Lymphocytes. Eosinophils.

There is 1 question to complete.