PATHOLOGY

PATHOLOGY MCQ

INFLAMMATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is true
A
Lymphocytes use cytokines to interact with macrophages and migrate to inflammatory site using adhesion molecules and chemokines
B
Eosinophils contain a protein toxic to bacteria and use eotaxin and adhesion molecules for extrastation
C
Mast cells live in the CT of areas with contact with the external environment
D
Mast cells produce cytokines contributing to fibrosis in chronic inflammation
Explanation: 

Detailed explanation-1: -Mast Cells and Immunoglobulin E Degranulation results in the release of inflammatory mediators (e.g., histamine, prostaglandins, leukotrienes, kinins, serotonin, heparin, and serine proteases).

Detailed explanation-2: -These mediators include histamine, neutral proteases, proteoglycans, and some cytokines, such as tumor necrosis factor-alpha (TNF-alpha). They are responsible for many of the acute signs and symptoms of mast cell-mediated allergic reactions, including edema, bronchoconstriction, and increased vascular permeability.

There is 1 question to complete.