A neonate born prematurely at 32-weeks gestationdevelops yellow skin and sclera (physiological jaundice).Laboratory studies show elevated serum levels of biliru-bin (breakdown product of heme). Inadequate bilirubinclearance by the liver in this neonate was most likelycaused by organ immaturity. What liver enzyme conju-gates serum bilirubin, making it water soluble, for excre-tion in the bile?

LIVER

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A neonate born prematurely at 32-weeks’ gestationdevelops yellow skin and sclera (physiological jaundice).Laboratory studies show elevated serum levels of biliru-bin (breakdown product of heme). Inadequate bilirubinclearance by the liver in this neonate was most likelycaused by organ immaturity. What liver enzyme conju-gates serum bilirubin, making it water soluble, for excre-tion in the bile?

A	Alanine aminotransferase
B	Aspartate transaminase
C	Fatty acyltransferase
D	Glucuronyltransferase
E	Galactosyltransferase

Explanation:

Detailed explanation-1: -Jaundice is caused by bilirubin deposition in the skin. Most jaundice in newborn infants is a result of increased red cell breakdown and decreased bilirubin excretion. Breastfeeding, haemolysis, and some metabolic and genetic disorders also increase the risk of jaundice.

Detailed explanation-2: -Physiological jaundice. The most common type of jaundice in newborns is physiological jaundice. Breastfeeding jaundice. Jaundice is more common in breastfed babies than formula-fed babies. Breast milk jaundice. Breast milk jaundice is different than breastfeeding jaundice. 17-Jan-2022

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PATHOLOGY

PATHOLOGY MCQ

LIVER