PATHOLOGY MCQ
LIVER
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Concentration of bile salts and pigments within thelumen of the gallbladder depends on active transportof Na+and HCO3-, as well as passive transport of H2O.Which of the following proteins facilitates the passivetransport of water across the plasma membrane of epi-thelial cells lining the gallbladder?
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Aquaporin
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Cadherin
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Occludin
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Perforin
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Porin
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Explanation:
Detailed explanation-1: -In the human liver, bile is composed of 97–98% water, 0.7% bile salts, 0.2% bilirubin, 0.51% fats (cholesterol, fatty acids, and lecithin), and 200 meq/L inorganic salts.
Detailed explanation-2: -Bile is a complex aqueous secretion that originates from hepatocytes and is modified distally by absorptive and secretory transport systems in the bile duct epithelium. Bile then enters the gallbladder where it is concentrated or is delivered directly to the intestinal lumen.
There is 1 question to complete.