PATHOLOGY

Detailed explanation-1: -The functional unit of the exocrine pancreas is composed of an acinus and its draining ductule (Figure 3). The ductal system extends from the lumen of the acinus to the duodenum. A ductule from the acinus drains into interlobular (intercalated) ducts, which in turn drain into the main pancreatic ductal system.

Detailed explanation-2: -The exocrine pancreatic component comprises  90% of the pancreatic mass and is comprised of acinar, centroacinar and ductal cells; the endocrine component islets of Langerhans comprise about 1-2% and the interstitium with the blood vessels, lymphatics, nerves and fibrous connective tissue stroma comprise the remainder.

Detailed explanation-3: -The pancreatic acinar cell is the functional unit of the exocrine pancreas. It synthesizes, stores, and secretes digestive enzymes. Under normal physiological conditions, digestive enzymes are activated only once they have reached the duodenum.

Detailed explanation-4: -The exocrine pancreas makes up the vast majority of pancreatic mass, which is mainly composed of acinar cells and ductal cells1, 2.