PATHOLOGY

Detailed explanation-1: -Hepatocytes (parenchymal cells) are the basic structural component of the liver, representing 60% of the total cell number and 80% of the total liver volume. They are arranged radially within the lobule to form cellular plates, between which the liver capillaries and the sinusoids are located.

Detailed explanation-2: -A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver’s mass.

Detailed explanation-3: -Primary human hepatocytes, human hepatic cancer cell lines, and human stem cell–derived hepatocyte-like cells are three main hepatic cell types used in current models and exhibit divergent hepatic phenotypes.