PATHOLOGY

Detailed explanation-1: -Liver lobules are collections of hepatocytes in a hexagonal shape with the center being a central vein. Within the lobules, the hepatocytes are arranged in cords, and in between the cords is a vascular space with a thin fenestrated endothelium and a discontinuous membrane called a sinusoid.

Detailed explanation-2: -The liver lobules are a roughly hexagonal arrangement of hepatocyte plates which are separated by intervening sinusoids (small blood vessels similar to capillaries but with a fenestrated endothelium) which radiate outward from a central vein. The portal triads are located at the vertices of each hexagon.

Detailed explanation-3: -Shaped like a cone, the liver is a dark reddish-brown organ that weighs about 3 pounds. There are 2 distinct sources that supply blood to the liver, including the following: Oxygenated blood flows in from the hepatic artery.

Detailed explanation-4: -The hepatic lobule is observed as a hexagon-like structure where the central vein is located at the center and the hepatocytes form radiating cords from the central vein, similar to the spokes of a wheel radiating from the central hub. At the outside “corners” of the hexagon are portal triads.