PATHOLOGY MCQ
LYMPHO RETICULAR SYSTEM
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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As the body ages the T & B cells become less responsive to ____
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Antigens
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Self tolerance
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Antibodies
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I mmunity
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Explanation:
Detailed explanation-1: -B cell structure and function During T cell-dependent activation, B cells absorb the antigen and then present pieces of the antigen on their surface via a major histocompatibility complex (MHC). Helper T cells can then recognize those antigens via the MHC and activate the B cells.
Detailed explanation-2: -The effects of aging on the immune system are manifest at multiple levels that include reduced production of B and T cells in bone marrow and thymus and diminished function of mature lymphocytes in secondary lymphoid tissues. As a result, elderly individuals do not respond to immune challenge as robustly as the young.
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