PATHOLOGY

PATHOLOGY MCQ

LYMPHO RETICULAR SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
As the body ages the T & B cells become less responsive to ____
A
Antigens
B
Self tolerance
C
Antibodies
D
I mmunity
Explanation: 

Detailed explanation-1: -B cell structure and function During T cell-dependent activation, B cells absorb the antigen and then present pieces of the antigen on their surface via a major histocompatibility complex (MHC). Helper T cells can then recognize those antigens via the MHC and activate the B cells.

Detailed explanation-2: -The effects of aging on the immune system are manifest at multiple levels that include reduced production of B and T cells in bone marrow and thymus and diminished function of mature lymphocytes in secondary lymphoid tissues. As a result, elderly individuals do not respond to immune challenge as robustly as the young.

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