PATHOLOGY MCQ
LYMPHO RETICULAR SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It makes T cells
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It makes B cells
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It makes tiny little soldiers
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It stops working as you age
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Detailed explanation-1: -The thymus is a primary lymphoid organ responsible for the production of immunocompetent T cells and, with aging, it atrophies and declines in functions. Universality of thymic involution in all species possessing thymus, including human, indicates it as a long-standing evolutionary event.
Detailed explanation-2: -The correct answer is c. The thymus is not involved in the production of either the B-cells or the T-cells. Only the T-cells are matured in the thymus after they are produced in the bone marrow by the hematopoietic process.
Detailed explanation-3: -The thymic epithelium starts to decrease as a main feature of age-related thymic involution from as early as the first year of human life at a rate of 3 % per year during adulthood, paralleling with an expansion of perivascular space that progressively fills with adipocytes and peripheral lymphocytes [15, 16].