PATHOLOGY

Detailed explanation-1: -Baroreceptors and mechanoreceptors respond to changes in pressure or stretch in blood vessels within the aortic arch and carotid sinus. In part, they can respond to changes in pH and changes in specific metabolites in the blood.

Detailed explanation-2: -Baroreceptors are stretch-sensitive fibers located primarily in the aortic arch and each of the carotid sinuses near the area where the common carotid artery bifurcates [10].

Detailed explanation-3: -Arterial baroreceptors function to inform the autonomic nervous system of beat-to-beat changes in blood pressure within the arterial system.