PATHOLOGY

Detailed explanation-1: -Acetylcholine also functions as a neurotransmitter in the autonomic nervous system, acting both as the neurotransmitter between preganglionic and postganglionic neurons as well as being the final release product from parasympathetic postganglionic neurons.[1]

Detailed explanation-2: -Acetylcholine is the neurotransmitter used at the neuromuscular junction-in other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles. This property means that drugs that affect cholinergic systems can have very dangerous effects ranging from paralysis to convulsions.

Detailed explanation-3: -Acetylcholine (ACh) is a fast-acting, point-to-point neurotransmitter at the neuromuscular junction and in the autonomic ganglia; however, there are fewer demonstrations of similar actions in the brain (Changeux, 2010).