PATHOLOGY

Detailed explanation-1: -Myelin can greatly increase the speed of electrical impulses in neurons because it insulates the axon and assembles voltage-gated sodium channel clusters at discrete nodes along its length.

Detailed explanation-2: -A protective covering called the myelin sheath, covers most neurons. Myelin insulates the axon and helps nerve signals travel faster and farther. Messages travel along a single neuron as electrical impulses, but messages between neurons travel differently.

Detailed explanation-3: -The myelin sheath is a greatly extended and modified plasma membrane wrapped around the nerve axon in a spiral fashion [1]. The myelin membranes originate from and are a part of the Schwann cells in the peripheral nervous system (PNS) and the oligodendroglial cells in the central nervous system (CNS) (see Chap. 1).