PATHOLOGY

Detailed explanation-1: -At a chemical synapse, an action potential triggers the presynaptic neuron to release neurotransmitters. These molecules bind to receptors on the postsynaptic cell and make it more or less likely to fire an action potential.

Detailed explanation-2: -Neurotransmitters are released from the axon terminal when their vesicles “fuse” with the membrane of the axon terminal, spilling the neurotransmitter into the synaptic cleft.

Detailed explanation-3: -Yes, the neurotransmitter is a chemical released from the presynaptic membrane, so it would open chemically gated channels on the postsynaptic membrane.