PATHOLOGY

PATHOLOGY MCQ

NERVOUS SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The steps below refer to various stages in transmission at a chemical synapse:1. Neurotransmitter binds with receptors associated with the postsynaptic membrane.2. Calcium ions rush into neuron’s cytoplasm.3. An action potential depolarizes the membrane of the axon terminal.4. The ligand-gated ion channels open.5. The synaptic vesicles release neurotransmitter into the synaptic cleft.Which sequence of events is correct?
A
3
B
1
C
5
D
4
E
2
Explanation: 

Detailed explanation-1: -I. Synthesis and Storage. II. Neurotransmitter Release. III. Neurotransmitter Postsynaptic Receptors. IV. Inactivation of Neurotransmitters. Types of Neurotransmitters.

Detailed explanation-2: -nerve impulse arrive at end bulb. depolarization opens voltage-gated calcium channels, calcium flows into axon terminal. triggers exocytosis of synaptic vesicles with neurotransmitter. neurotransmitter released into synaptic cleft and diffuse. bind to receptors on postsynaptic neuron and opens ligand-gated channels. More items

Detailed explanation-3: -AP arrives at axon terminal of presynaptic neuron. Voltage-gated Ca2+ channels open and Ca2+ enters axon terminal. Ca2+ entry causes synaptic vesicles to release neurotransmitter. Neurotransmitter diffuse across the synaptic cleft and binds to specific receptors on the post synaptic membrane. More items

There is 1 question to complete.