PATHOLOGY

Detailed explanation-1: -The sciatic nerve is the longest, largest nerve in your body. Your sciatic nerve roots start in your lower back and run down the back of each leg. Sciatica is the pain or discomfort if your sciatic nerve gets compressed or pinched.

Detailed explanation-2: -The main nerve traveling down the leg is the sciatic nerve. Pain associated with the sciatic nerve usually originates higher along the spinal cord when nerve roots become compressed or damaged from narrowing of the vertebral column or from a slipped disk.

Detailed explanation-3: -The five nerve roots come together to form a right and left sciatic nerve. On each side of your body, one sciatic nerve runs through your hips, buttocks and down a leg, ending just below the knee.