PATHOLOGY

Detailed explanation-1: -Thus, the results suggested that action potentials initiate in the axon at some distance from the soma and that the local density of Na+ channels in the axon hillock/initial segment, which is not high, does not determine the lowest threshold of the neuron for action-potential initiation.

Detailed explanation-2: -A typical action potential begins at the axon hillock with a sufficiently strong depolarization, e.g., a stimulus that increases Vm.

Detailed explanation-3: -The axon hillock is the last site in the soma where membrane potentials propagated from synaptic inputs are summated before being transmitted to the axon.

Detailed explanation-4: -The axon hillock is the location in the cell between the cell body and the axon where the action potential starts.