PATHOLOGY

Detailed explanation-1: -When fats and proteins enter your small intestine, cholecystokinin triggers your gallbladder and pancreas to contract. They deliver bile and enzymes to your duodenum to help break down the food for absorption.

Detailed explanation-2: -CCK triggers bile release from the gallbladder and the secretion of digestive enzymes from the pancreas [1, 22–27]. Fig. (2). Effect of diet on the release of cholecystokinin (CCK) for the regulation of hepatobiliary and pancreatic functions and gastrointestinal tract motility.

Detailed explanation-3: -Cholecystokinin is secreted by cells of the upper small intestine. Its secretion is stimulated by the introduction of hydrochloric acid, amino acids, or fatty acids into the stomach or duodenum.

Detailed explanation-4: -Cholecystokinin (CCK) is released from mucosal endocrine cells in the proximal small intestine in response to a meal[1], and it is classically known to stimulate the gallbladder contraction.