PATHOLOGY

Detailed explanation-1: -Nuclease is also called nucleo depolymerase. The breakdown of nucleic acid into nucleotides is done by cleaving the phosphodiester bond which is present between the nucleotides in the nucleic acids.

Detailed explanation-2: -Nucleases come in and cleave these nucleotides apart from one another. Exonucleases cut off the ends of RNA and DNA sequences, and endonucleases cut small sequences out of the middle of DNA and RNA sequences. Restriction nucleases, a type of endonuclease, can help to ‘kill’ viruses.

Detailed explanation-3: -Nucleases cleave the phosphodiester bonds of nucleic acids and may be endo or exo, DNases or RNases, topoisomerases, recombinases, ribozymes, or RNA splicing enzymes.