PATHOLOGY MCQ
SKIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It relies on folate
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It doesn’t you must use sunscreen
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it activates vitamin D3 production which takes care of that
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Forms a protective cap over the nucleus of skin cells
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Detailed explanation-1: -Melanin synthesized within melanosomes is transported via dendrites to adjacent keratinocytes, and accumulate within keratinocytes and melanocytes in the perinuclear area as supranuclear “caps” that are thought to shield DNA from UV rays (58).
Detailed explanation-2: -In most people, UV rays activate a chemical in the skin called melanin. This is the skin’s first defense against the sun. Melanin absorbs the dangerous UV rays that can do serious skin damage. This is the process that gives you a tan.
Detailed explanation-3: -The skin’s natural defence to this radiation is to produce melanin (brown pigment), in order to protect the DNA in the nucleus. The melanin reflects UV radiation in order to protect the interior of the cells from changes to their DNA. Damage to DNA from UV radiation can cause cancer or harmful mutations.