PATHOLOGY

Detailed explanation-1: -Meissner corpuscles consist of a cutaneous nerve ending responsible for transmitting the sensations of fine, discriminative touch and vibration. [1] Meissner corpuscles are most sensitive to low-frequency vibrations between 10 to 50 Hertz and can respond to skin indentations of less than 10 micrometers.

Detailed explanation-2: -Meissner’s corpuscles, also known as tactile corpuscles, are found in the upper dermis, but they project into the epidermis. They are found primarily in the glabrous skin on the fingertips and eyelids. They respond to fine touch and pressure, but they also respond to low-frequency vibration or flutter.

Detailed explanation-3: -Meissner’s corpuscles, which lie between the dermal papillae just beneath the epidermis of the fingers, palms, and soles, are elongated receptors formed by a connective tissue capsule that comprises several lamellae of Schwann cells.

Detailed explanation-4: -These receptors include Meissner’s corpuscles, Pacinian corpuscles, Merkel’s disks, and Ruffini corpuscles. Meissner’s corpuscles respond to pressure and lower frequency vibrations, and Pacinian corpuscles detect transient pressure and higher frequency vibrations.