PATHOLOGY

Detailed explanation-1: -Sensations begin as signals generated by touch receptors in your skin. They travel along sensory nerves made up of bundled fibers that connect to neurons in the spinal cord. Then signals move to the thalamus, which relays information to the rest of the brain.

Detailed explanation-2: -3. Specialized Receptors in the Skin Send Touch Signals to the Brain. Skin consists of three major tissue layers: the outer epidermis, middle dermis, and inner hypodermis. Specialized receptor cells within these layers detect tactile sensations and relay signals through peripheral nerves toward the brain.

Detailed explanation-3: -Free nerve endings called nociceptors in the skin have a high threshold for mechanical, chemical, or thermal stimuli and respond only when the intensity of these stimuli is high enough to damage tissue. We perceive the input from these receptors as pain.