PATHOLOGY

Detailed explanation-1: -Taste buds are sensory end organs that are located in the oral epithelium (BOX 1). The receptors on the chemosensitive apical tips of taste bud cells confer specificity to gustatory stimuli. Taste receptors come in many types, including several classes of G protein-coupled receptors (GPCRs) and ion channels (FIG. 1).

Detailed explanation-2: -A cluster of approximately 50 receptors comprises a taste bud. These receptor cells are renewed approximately every 10 days. Taste buds bind the specific chemical components of food dissolved in saliva.