PATHOLOGY

Detailed explanation-1: -Differences in skin pigmentation result both from the relative ratio of eumelanin (brown–black) to pheomelanin (yellow–red), as well as the number of melanosomes within melanocytes.

Detailed explanation-2: -There are two types of melanin in mammals, the brownish black eumelanin and the reddish yellow pheomelanin. Eumelanin and pheomelanin are present in human hair and this study was carried out to see whether both pigments are also present in human epidermis.

Detailed explanation-3: -There are two major pigment types present in the skin: eumelanin and pheomelanin. Each is made exclusively in melanocytes and each derives from the amino acid tyrosine, which is oxidized and cyclized through the actions of tyrosinase and other pigment enzymes (Fig. 6).