PATHOLOGY

Detailed explanation-1: -Pigmentation of the skin results from the accumulation of melanin-containing melanosomes in the basal layer of the epidermis. Differences in skin pigmentation result both from the relative ratio of eumelanin (brown–black) to pheomelanin (yellow–red), as well as the number of melanosomes within melanocytes.

Detailed explanation-2: -Although melanin is usually discussed as a single pigment, there are two types of melanin that contribute to pigmentation in the hair, skin, and eyes of humans and animals: Eumelanin. This pigment is associated with dark tones, such as brown and black.