PATHOLOGY

Detailed explanation-1: -The second layer of skin is the dermis. The dermis contains hair follicles, sweat glands, sebaceous (oil) glands, blood vessels, nerve endings, and a variety of touch receptors.

Detailed explanation-2: -The skin possesses many sensory receptors in the epidermis, dermis, and hypodermis, which allows for discrimination of touch such as pressure differences (light vs. deep). Other qualities of the external world assessed by skin sensory receptors includes temperature, pain, and itch.

Detailed explanation-3: -We can feel different modalities of touch because of the presence of specialized sensory receptors, called mechanoreceptors, located in the skin. The Pacinian corpuscles are located deep in the dermis of the skin and are responsible for perception of vibration.

Detailed explanation-4: -The dermis layer also contains pain and touch receptors that transmit sensations of pain, itch, pressure and information regarding temperature to the brain for interpretation.