PATHOLOGY MCQ
TUMOURS GENERAL FEATURES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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VHL gene mutation
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Monosomy 1
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Trisomy 7 & 17
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Hypodiploidy
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Detailed explanation-1: -Papillary renal cell tumours are characterized by trisomy of chromosomes 7 and 17. Trisomy of chromosomes 7 and 17 occurs in all cytological variation of papillary renal cell tumours at similar frequency irrespectively of grade or size.
Detailed explanation-2: -Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) HLRCC is a hereditary syndrome that increases the risk of kidney cancer. HLRCC is associated with a unique type of kidney cancer that can be fast growing and may lead to different treatment decisions.
Detailed explanation-3: -Though the exact cause of Papillary renal cell carcinoma is unknown, smoking, obesity, and genetic predisposition conditions (such as hereditary leiomyomatosis and renal cell cancer) may contribute to the development of this type of cancer."