PATHOLOGY

Detailed explanation-1: -Chromophobe RCCs reportedly have the best prognosis of all of the different RCC subtypes, with a 5-year survival rate of over 90%, as opposed to clear cell and papillary RCCs, which have rates of survival of 55– 60% and 80–90%, respectively [2–4].

Detailed explanation-2: -Papillary and chromophobe types of renal cell carcinoma have a better prognosis because they are often low grade. Collecting duct carcinoma and renal medullary carcinoma have a poor prognosis because they are often very aggressive.

Detailed explanation-3: -This four-tiered grading system allows classification of ChRCC tumors as grade 1 (very low risk), grade 2 (low risk), grade 3 (similar histology to grade 2 plus necrosis; intermediate risk), or grade 4 (high risk; Fig. 1).