..... are specialized epithelial cells of the distal convoluted tubule. These cells sense sodium chloride concentration in the tubule, which in turn reflects the systemic blood pressure.

URINARY SYSTEM

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

____ are specialized epithelial cells of the distal convoluted tubule. These cells sense sodium chloride concentration in the tubule, which in turn reflects the systemic blood pressure.

A	Podocytes
B	Juxtaglomerular cells
C	Mesangial cells
D	Macula densa

Explanation:

Detailed explanation-1: -The cells of the macula densa are sensitive to the concentration of sodium chloride in the distal convoluted tubule.

Detailed explanation-2: -The macula densa is a group of 15 to 20 cells that form the thickening on the surface of the distal convoluted tubule. This region is situated between the ascending limb of Henle’s loop and distal convoluted tubule. It is an area where the distal convoluted tubule is in direct contact with glomerulus.

Detailed explanation-3: -Increased sodium chloride delivery to the macula densa causes release of adenosine, which then binds to the afferent arteriole causing vasoconstriction. This vasoconstriction subsequently decreases GFR. The opposite response occurs because of decreases in sodium chloride delivery to the macula densa.

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PATHOLOGY

PATHOLOGY MCQ

URINARY SYSTEM