PATHOLOGY

Detailed explanation-1: -ADH is secreted by pituitary gland. It increases the water permeability of distal convoluted tubules and collecting tubules, hence, plays a significant role in water re-absorption. The absence of ADH will reduce water reabsorption which may lead to water diuresis or diabetes insipidus.

Detailed explanation-2: -ADH increases water reabsorption by increasing the nephron’s permeability to water, while aldosterone works by increasing the reabsorption of both sodium and water.

Detailed explanation-3: -ADH increases the permeability to water of the distal convoluted tubule and collecting duct, which are normally impermeable to water. This effect causes increased water reabsorption and retention and decreases the volume of urine produced relative to its ion content.