PATHOLOGY

Detailed explanation-1: -Increasing the concentration of carbon dioxide in the blood therefore results in more H+ ions and a lower pH. However, both these reactions are reversible, and breathing heavily to remove carbon dioxide from the body will lead to a reduction in the concentration of the H+ and HCO3-ions, and hence to an increase in pH.

Detailed explanation-2: -As carbon dioxide accumulates in the blood, the pH of the blood decreases (acidity increases). The brain regulates the amount of carbon dioxide that is exhaled by controlling the speed and depth of breathing (ventilation).

Detailed explanation-3: -When the CO2 level is high, the concentration of hydrogen ions in the bloodstream rises due to the formation of carbolic acid. It leads to the lowering of pH and results in acidosis. Thus, the cerebrospinal fluid attains acidic nature when carbon dioxide increases in the bloodstream.