PATHOLOGY

Detailed explanation-1: -Aldosterone secretion from the adrenal cortex in the zona glomerulosa.[18][19]This is mediated through the transcription of CYP11B2 (aldosterone synthase)[20] Increase sodium reabsorption through increased activity of the Na-H antiporter in the proximal convoluted tubule (PCT)[21]

Detailed explanation-2: -Angiotensin II also triggers your adrenal glands to release aldosterone and your pituitary gland to release antidiuretic hormone (ADH, or vasopressin). Together, aldosterone and ADH cause your kidneys to retain sodium. Aldosterone also causes your kidneys to release (excrete) potassium through your urine.

Detailed explanation-3: -It is concluded that endogenous brain angiotensin II participates in central mechanisms of blood pressure regulation by the stimulation of the release of antidiuretic hormone, adrenocorticotrophic hormone, adrenaline and noradrenaline.

Detailed explanation-4: -Angiotensin II (AngII) evokes a variety of physiological responses in the adrenal gland. It is the major regulator of aldosterone secretion, in the medulla it enhances catecholamine release and it exerts trophic effects in the adrenal and stimulates growth factor secretion.