PATHOLOGY

Detailed explanation-1: -Podocytes make up the epithelial lining of Bowman’s capsule, the third layer through which filtration of blood takes place. Bowman’s capsule filters the blood, retaining large molecules such as proteins while smaller molecules such as water, salts, and sugars are filtered as the first step in the formation of urine.

Detailed explanation-2: -Podocytes play an important role in glomerular function. Together with endothelial cells of the glomerular capillary loop and the glomerular basement membrane they form a filtration barrier. Podocytes cooperate with mesangial cells to support the structure and function of the glomerulus.