PATHOLOGY

Detailed explanation-1: -Most of the solutes get reabsorbed in the PCT by a process called tubular reabsorption. In the loop of Henle, the filtrate continues to exchange solutes and water with the renal medulla and the peritubular capillary network. Water is also reabsorbed during this step.

Detailed explanation-2: -Water reabsorption occurs in the thin descending limb of the Loop of Henle. It is permeable to water, which means that H2O molecules are freely able to leave it. Similarly to in the PCT, water can leave the thin descending limb into the more concentrated medulla through transcellular and paracellular movement.

Detailed explanation-3: -About 67 percent of the water, Na+, and K+ entering the nephron is reabsorbed in the PCT and returned to the circulation. Almost 100 percent of glucose, amino acids, and other organic substances such as vitamins are normally recovered here.