PATHOLOGY

Detailed explanation-1: -Urea is one of the waste products found in urine. It’s a byproduct of the breakdown of protein and can be broken down further to ammonia in certain situations. Therefore, many conditions that result in concentrated urine can cause urine that smells like ammonia.

Detailed explanation-2: -Ammonia is produced from leftover amino acids, and it must be removed from the body. The liver produces several chemicals (enzymes) that change ammonia into a form called urea, which the body can remove in the urine.

Detailed explanation-3: -Ammonium Generation and Excretion Ammonia (NH3) is predominantly generated from the metabolism of glutamine in the kidney through the process of ammoniagenesis. Glutamine is synthesized in the liver and transported via circulation to kidney proximal tubule, where it is taken up by specific transporters [15].