PATHOLOGY MCQ
URINARY SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The ascending limb of the loop of Henle functions to:
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remove water and additional solutes.
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help regulate aldosterone secretion.
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increase the rate of active transport of Na+ in the distal tubules and collecting ducts.
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dilute the filtrate by removing solutes.
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Explanation:
Detailed explanation-1: -A: The ascending limb of the loop of Henle functions to dilute the filtrate by removing solutes. The thin segment of the ascending limb is not permeable to water, but it is permeable to solutes.
Detailed explanation-2: -The ascending limb of Henle’s loop is impermeable to water but permeable to electrolytes. As a result, the filtrate gets diluted as it moves up the ascending limb of Henle’s loop.
Detailed explanation-3: -Water present in the filtrate in the papillary duct flows through aquaporin channels out of the duct, moving passively down its concentration gradient. This process reabsorbs water and creates a concentrated urine for excretion.
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